Hairy cell leukaemia
Rare but often very treatable with the purine analogue cladrabine
Look long and hard for them in all patients with cytopenia(s) especially where there is also splenomegaly
These lymphocytes:
- are medium sized
- have fine irregular projections
- contain a condensed nuclear chromatin structure and absent nucleoli
- are often very few in the peripheral blood
What is the classical pattern by immunophenotyping/flow cytometry?
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