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Patient

34-year-old male

Clinical details

Mouth ulcers and abnormal blood count

Patient Automated blood count

Hb 104 g/L
WCC 19.2 x 109/L
PLT 56 x 109/L

Hb-haemoglobin, WCC-white cell count, PLT-platelet count

  1. Provide a combined report of the blood film, bone marrow aspirate and immunophenotyping results.
  2. What are the likely associated genetic changes? 
  3. Provide a brief management plan regarding therapy and monitoring?

Blood film

Bone marrow aspirate

Immunophenotyping (flow cytometry)

Other markers

  • Positive expression – MPO, CD33
  • Negative expression – CD34, HLA-DR